Colon cancer symptoms, causes and treatment

What are the symptoms, causes and treatment methods of colon (bowel) cancer?

Colon cancer is a type of cancer that begins with abnormal cell growth in the inner walls of the colon or rectum. This type of cancer can be treated if diagnosed early, but in advanced cases, it can lead to serious health problems. Risk factors include genetic predisposition, age, poor dietary habits, obesity, and smoking. Treatment options include surgical intervention, chemotherapy, and radiotherapy.

What is Colon (Bowel) Cancer?

Colon cancer is a type of cancer that develops from uncontrolled cell growth in the last part of the large intestine. It usually develops from polyps. Regular screenings allow the disease to be caught in its early stages.

What are the Causes and Risk Factors of Colon (Bowel) Cancer?

Many factors play a role in the development of colon cancer. The most common causes are:

  • Age: More common in people aged 50 and older.
  • Genetic Factors: A family history of colon cancer increases the risk.
  • Immune System Problems: Intestinal diseases such as Crohn’s disease and ulcerative colitis increase the risk.
  • Dietary Habits: Diets low in fiber, high in processed foods and red meat have negative effects.
  • Obesity and Inactivity: Being overweight and lack of physical activity are significant risk factors.
  • Smoking and Alcohol Consumption: May increase the risk of colon cancer.

Healthy eating and regular exercise can reduce these risks.

How Many Stages are There in Colon (Bowel) Cancer?

Colon cancer is evaluated in 5 stages (from Stage 0 to Stage 4). Each stage is determined based on the extent of cancer spread:

Stage 0 (Carcinoma in situ)

  • Cancer cells are only found in the inner lining of the colon (mucosal layer).
  • It has not spread to deeper tissues or lymph nodes yet.
  • If diagnosed early, it can be completely removed.

Stage 1

  • The cancer has spread deeper into the inner lining of the colon but has not spread to the lymph nodes or distant organs.
  • Surgical treatment can yield successful results.

Stage 2

  • The cancer has spread further into the deeper layers of the colon but has not yet spread to the lymph nodes.
  • It may sometimes spread to surrounding tissues.
  • Treatment usually includes surgery, and sometimes chemotherapy as well.

Stage 3

  • The cancer has spread to the lymph nodes but has not spread to distant organs (such as liver, lungs, etc.).
  • The treatment process typically includes surgery, chemotherapy, and sometimes radiotherapy.

Stage 4 (Metastatic Stage)

  • The cancer has spread beyond the lymph nodes to distant organs.
  • It most commonly metastasizes to the liver, lungs, or abdominal lining.
  • Treatment typically includes chemotherapy, targeted therapy, and sometimes surgery, but the goal is usually to control the disease and extend life expectancy.

What Are the Symptoms of Colon (Bowel) Cancer?

Colon cancer may not show symptoms in the early stages. However, as the disease progresses, some symptoms may appear:

  • Changes in bowel habits (diarrhea, constipation, or narrowing of stool)
  • Blood in the stool or dark-colored stool
  • Abdominal pain, cramps, and gas complaints
  • Unexplained weight loss
  • Persistent fatigue and weakness
  • A feeling that the bowels are not completely empty

If these symptoms persist for a long time, it is important to consult a doctor.

What Are the Diagnostic Methods for Colon (Bowel) Cancer?

Early diagnosis increases treatment success. The most common diagnostic methods are:

  • Colonoscopy: Used to examine the colon in detail. If polyps are detected, they can be removed.
  • Fecal Tests: Used to screen for hidden blood and determine the presence of abnormal cells.
  • CT Colonography: Uses computerized tomography to visualize the intestines.
  • Biopsy: A sample is taken from suspicious tissues for laboratory examination.

Regular screening tests are vital for early diagnosis.

What Are the Treatment Methods for Colon (Bowel) Cancer?

The treatment plan is determined based on the stage of the disease and the patient’s general health condition. The most common treatment methods are:

  1. Surgical Intervention

In cases where cancer is in the early stages, the affected part of the colon can be surgically removed. Methods such as polypectomy, local excision, and colectomy are used.

  1. Chemotherapy

Medication is used to destroy cancer cells or stop their growth. It may be used before or after surgery.

  1. Radiotherapy

High-energy radiation is used to target cancerous cells. It is generally preferred for rectal cancer treatment.

  1. Targeted Therapy

Biological agents are used to prevent the growth of cancer cells. This treatment is typically applied to advanced-stage patients.

  1. Immunotherapy

Medications that help the immune system fight cancer cells are used. It may be effective in patients with genetic mutations.

The treatment process should be planned with a multidisciplinary approach.

What Are the Prevention Methods for Colon (Bowel) Cancer?

The risk of colon cancer can be significantly reduced with the following healthy lifestyle habits:

  • Eat a diet rich in fiber (vegetables, fruits, whole grains)
  • Reduce the consumption of processed foods and red meat
  • Engage in regular physical exercise
  • Maintain an ideal weight
  • Avoid smoking and alcohol consumption
  • Participate in regular screening tests

Minimizing risk factors is the most effective method of preventing the disease.

Frequently Asked Questions About Colon (Bowel) Cancer

  1. At what age group is colon (bowel) cancer more common?

It is more common in individuals aged 50 and older. However, the incidence in younger individuals is also increasing.

  1. Is colon (bowel) cancer genetic?

Individuals with a family history of colon cancer are at higher risk. Genetic testing can be used for risk assessment.

  1. If colon (bowel) cancer is diagnosed early, can it be treated?

Yes, if diagnosed in the early stages, the success rate of treatment is quite high.

  1. Do polyps always turn into colon (bowel) cancer?

No, but some types of polyps can turn into cancer over time. Therefore, regular check-ups are important.

  1. Can colon (bowel) cancer be completely prevented?

Although it cannot be completely prevented, a healthy lifestyle and regular screening tests can significantly reduce the risk.

Sources:
  • National Cancer Institute (NCI)
  • American Cancer Society (ACS)
  • Mayo Clinic
  • Memorial Sloan Kettering Cancer Center
  • Johns Hopkins Medicine
  • MD Anderson Cancer Center
  • Cleveland Clinic
  • Stanford Medicine
  • Harvard Health Publishing
  • Cancer Research UK