Stem Cell Treatment

STEM CELLS

Some cells in the human body have the ability to renew themselves and transform into different cell types. These cells, called STEM CELLS, can divide and multiply, unlike muscle and nerve cells, which do not have the ability to proliferate. The stem cell, which enables the formation of millions of cells from a single cell, can also multiply by dividing in order to renew itself.

Although stem cells cannot provide O2 transport, hormonal and neural transmission, they play a role in the formation of cells that will perform these vital functions. The stem cell, which has the ability to renew itself throughout a lifetime, differentiates in parallel with the needs of the body and enables other cells to develop and proliferate. However, as we age, the amount of stem cells in the body gradually decreases.

While 1 in every ten thousand cells in newborns is a stem cell, after the age of 65, only one in a million cells is a stem cell. Since the number of stem cells decreases with advancing age, damaged tissues and organs cannot be repaired. Therefore, stem cell therapy can make great contributions to the treatment of many diseases that progress rapidly in older ages, some cancers and congenital blood diseases.

TYPES OF STEM CELLS

  • Embryonic Stem Cells
  • Adult Stem Cells (Capable of Regenerating Adult Tissues)
  • Hematopoietic Stem Cells
  • Mesenchymal Stem Cells
  • Endothelial Stem Cells
  • Induced Pluripotent Stem Cells

 

Embryonic Stem Cells

Stem cells with different types help create organs and tissues while in the mother’s womb. These are called embryonic stem cells. They repair organ and tissue damage caused by disease, injury, and other reasons.

Embryonic stem cells are found in embryos and are totipotent cells with the ability to turn into all cell types in adults. They transform into the required cell type. They also play a role in the formation of stem cells of the same type due to their property of division.

Somatic–Pluripotent Stem Cell

Unlike embryonic stem cells, there are also somatic stem cells in the body. In addition to tissue-specific or adult stem cells, there are also other stimulated stem cells. Pluripotent (IPS) cells are among them.

These stem cells taken from adipose tissue or bone marrow can be used to treat many diseases by transplanting them to another person. They can be given through the bloodstream or directly transplanted into the damaged organ. When stem cells enter the patient’s body, they grow and turn into other cells that the organism needs, repairing diseased tissues or organs.

Mesenchymal Stem Cells

Mesenchymal stem cells show the ability to differentiate into the musculoskeletal system. Mesenchymal stem cells; They can be obtained in the laboratory from bone marrow, synovium, fat tissue, amniotic source, peripheral blood and allogeneic adult tissue.

STEM CELL TREATMENT

It is a treatment method used to regenerate the patient’s damaged cells, tissues and organs by transplanting stem cells taken from the person or a donor to sick people. While treatment was previously performed only with stem cells taken from the bone marrow, today they can also be taken from peripheral blood, umbilical fat, and even baby cord blood. In addition, recently stem cells can be obtained from eggs (embryonic stem cells) and fat tissue.

Bone Marrow Derived Stem Cell Therapy

Bone Marrow Treatment Indications

  1. Heart, brain and nerve diseases
  2. In cases of congenital abnormalities arising from the metabolic or enzymatic system
  3. Healing diseased or damaged bone marrow
  4. Relieving pressure on the immune system
  5. Healing damaged tissues and organs

STEM CELL INDICATION

NEURODEGENERATIVE DISEASES
  1. Diseases such as Alzheimer’s, Parkinson’s, and Multiple Sclerosis
  2. Spinal cord injuries
  3. Strokes caused by blocked blood vessels in the brain

While stem cells may not be effective in repairing damaged areas within the brain for some diseases and injuries, they can activate healthy brain tissue to promote healing.

SYSTEMIC AND MISCELLANEOUS DISEASES
  1. Congestive heart diseases
  2. Lung disease (COPD)
  3. Diabetes Mellitus
  4. Erectile Dysfunction
  5. Macular Degeneration
  6. Alopecia (Local baldness)
  7. Peripheral artery diseases (Burger)
HEMATOLOGICAL DISEASES
  1. Bone marrow cancers
  2. Lymphoma- Hodgkin lymphoma
  3. Leukemia-Multiple myeloma
  4. Mediterranean anemia
  5. Plasma cell diseases
  6. Bone marrow failure
  7. Hereditary and congenital blood diseases
MUSCLE SKELETAL SYSTEM DISEASES
  1. Osteoarthritis (Wear and tear on the joint)
  2. Meniscus problems in the knees
  3. Tendon and ligament problems
  4. Muscle diseases
  5. Various injuries (Trauma-sports)
  6. Rheumatic Diseases (SLERA)
Cosmetic Applications
  • Skin rejuvenation and tightening
  • Hand cosmetics
  • Facial bone and soft tissue trauma
  • Maxillofacial surgery applications
  • Hair restoration- Hair loss
  • Plastic surgery applications
  • Surgical wound repair
  • Reconstructive applications (Breast etc.)
  • Repair of burns, injuries and scars

Preparation of PRP

PRP (Platelet Rich Plasma) is made by separating the blood taken from the patient with a special process. The plasma obtained after this procedure contains rich platelets. Platelets secrete growth factors that promote healing. Therefore, PRP treatment helps heal damaged tissues. PRP is often used to treat the following diseases:

  • Tendinitis
  • Ligament damage
  • Muscle injuries
  • Cartilage damage

Differences between stem cells and PRP

Stem cell therapy has a longer-lasting effect than PRP therapy. Stem cells support healing by starting to regenerate in damaged tissue.

PRP treatment has a faster effect, but its effect lasts shorter. Generally, PRP treatment is preferred for mild to moderate diseases, and stem cell treatment is preferred for more severe diseases.

  • Stem cell therapy is performed by using live stem cells injected into damaged tissues.
  • PRP treatment provides healing with the growth factors secreted by platelets.
  • Stem cell therapy is a more invasive procedure because stem cells are often obtained from bone marrow or fat tissue and undergo special processing before being injected.
  • PRP treatment is injected after the blood is separated.
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