- May 19, 2025
- Web Editorial Board
- Health Guide, Treatment Methods and Operations
ThuFLEP Prostate Surgery
Prostate surgery with ThuFLEP is a modern, minimally‑invasive option for men with benign prostatic hyperplasia (BPH). It uses advanced laser energy to separate and remove prostate tissue along the natural anatomical plane, shortening hospital stay and reducing bleeding risk.
What Is ThuFLEP?
ThuFLEP (Thulium Fiber Laser Enucleation) is an endoscopic procedure that employs a continuous 1‑µm laser beam to peel prostate tissue almost bloodlessly and evacuate it from the bladder. Its shallow penetration depth minimizes the risk of damage to surrounding structures.
Who Is a Candidate for ThuFLEP?
- Patients with BPH who do not respond to medication or experience side effects
- Individuals taking anticoagulants who face a high bleeding risk with open surgery
- Men with prostate volumes above 30 mL and significantly reduced urinary flow
- Those with recurrent urinary tract infections, bladder stones, or kidney impairment
How Is ThuFLEP Performed?
- Endoscopic Access: The surgeon advances a cystoscope through the urethra and illuminates the field.
- Laser Tissue Removal: Using a TFL probe, prostate tissue is separated from the capsule in thin layers.
- Tissue Morcellation & Extraction: The detached tissue is vacuum‑suctioned with a morcellator.
- Short Catheterization: The catheter is typically removed within 24 hours, after which the patient goes home.
Key Advantages of ThuFLEP
- Very Low Bleeding Risk: Continuous energy coagulates vessels as it cuts.
- General or Spinal Anesthesia Options: Adaptable to different health profiles.
- Effectiveness in Large Prostates: High success reported in glands up to 250 mL.
- One‑Session Definitive Treatment: Complete tissue removal keeps reoperation rates below 7 %, similar to HoLEP.
Disadvantages and Possible Side Effects
- Temporary urinary incontinence or urgency in the first weeks
- Risk of retrograde ejaculation (semen flows into the bladder)
- Rarely, temporary erectile dysfunction or urethral stricture
Recovery Timeline After ThuFLEP
- 1–3 Days: Mild pink urine is normal; drink plenty of water.
- 1 Week: Return to desk work is possible; avoid strenuous exercise.
- 3–4 Weeks: Cycling and weight lifting can be re‑introduced gradually.
- 4–6 Weeks: Sexual activity may resume once your surgeon approves.
Comparison of ThuFLEP, HoLEP and Other Laser Methods
| Feature | ThuFLEP | HoLEP | GreenLight (PVP) |
|---|---|---|---|
| Bleeding rate | Very low | Low | Low |
| Tissue removal | Complete removal | Complete removal | Surface vaporization |
| Prostate size limit | ~250 mL+ | ~300 mL+ | Generally < 80 mL |
| Recurrence risk (5 years) | ≤ 7 % | ≤ 7 % | 10–15 % |
Frequently Asked Questions About ThuFLEP
1- Is ThuFLEP painful?
The procedure is performed under general or spinal anesthesia. Mild burning afterward is typically managed with acetaminophen.
2- When is the catheter removed?
In most patients, the catheter is taken out within the first 24 hours.
3- When can I return to work?
Desk work is often possible after 5–7 days; physically demanding jobs after 3–4 weeks.
4- Is retrograde ejaculation permanent?
It is permanent in most men, but sexual pleasure is generally unaffected.
5- What is the chance of needing repeat surgery?
Less than 7 % within five years of follow‑up.
6- Is ThuFLEP effective in very large prostates?
High success rates are reported even for glands over 250 mL.
7- Is blood in urine normal after surgery?
Pinkish urine for the first 1–3 days is expected. Contact your doctor if you see clots.
8- When can I resume sports?
Walking is encouraged from day one; heavy exercise after 3–4 weeks.
9- Which is better, ThuFLEP or HoLEP?
Success and complication rates are similar; choice depends on prostate size, surgeon experience, and available equipment.
10- Will my prostate grow again after laser surgery?
If the tissue is completely removed, regrowth is minimal, though age‑related hormonal changes continue.
11- What Is the Cost of ThuFLEP?
Prices vary with hospital class, equipment, insurance coverage, and prostate size. Please contact our facility for an exact quote. This article is for informational purposes only and does not replace medical advice.
Sources
- Mayo Clinic
- Cleveland Clinic
- Johns Hopkins Medicine
- European Association of Urology
- American Urological Association
- National Health Service (UK)
- Urology Care Foundation
- Journal of Endourology
- European Urology
- ScienceDirect
- Boston Scientific
- Urology Times
- Medscape
- PubMed (NIH)
- Harvard Health

