Varicocele: Causes, Symptoms and Treatment

Varicocele: Causes, Symptoms, and Treatment

Varicocele is a condition caused by the enlargement of the veins (venous dilation) in the scrotum and is one of the leading causes of male infertility. Early diagnosis and appropriate treatment are important for improving sperm quality and controlling pain.

What is Varicocele?

Varicocele refers to varicose-like vein enlargements in the testicles. It is most commonly seen in the left testicle and can lead to a decrease in testicular volume, increased temperature, and impaired sperm production over time.

What are the Symptoms?

The following symptoms may occur in varicocele:

  • A feeling of heaviness or aching in the testicle
  • Increased pain while sitting or exercising
  • A twisted bunch of veins noticeable by hand or visually
  • Abnormalities in sperm count, motility, or morphology in semen analysis

What Causes It?

Possible causes of varicocele include:

  • Valve insufficiency in the testicular veins
  • Longer and higher-pressure venous structure on the left side due to anatomical reasons
  • Increased intra-abdominal pressure caused by chronic constipation or frequent heavy lifting

How is it Diagnosed?

To diagnose varicocele, your doctor will first ask about your symptoms and then perform a physical examination of the testicles. Your doctor may ask you to stand, sit, or strain as if having a bowel movement (Valsalva maneuver). These maneuvers help detect any vein enlargement and lead to a clinical diagnosis.

To support the diagnosis, determine the severity, and plan surgery, a scrotal Doppler ultrasound may be performed.

Additionally, semen analysis and blood tests help assess whether varicocele is affecting your reproductive health.

How is it Treated?

Treatment depends on the severity of the condition. In asymptomatic or mild reflux cases, regular monitoring is recommended.

Surgery, specifically varicocelectomy, is advised in cases of pain, testicular shrinkage, or abnormal sperm parameters.

What is Varicocele Surgery (Varicocelectomy)?

Varicocelectomy is a surgical procedure to remove the swollen veins (varicoceles) inside the scrotum.

What Are the Types of Varicocelectomy?

Here are some types of varicocelectomy that your doctor may recommend:

Open Surgery

In open varicocele surgery, your surgeon makes a 2–3 cm incision in the groin area to locate and ligate the enlarged testicular veins.

Minimally Invasive Surgery

During minimally invasive surgery, your surgeon uses techniques that cause less damage to the skin and tissues. Minimally invasive varicocelectomy procedures include:

Laparoscopic Varicocelectomy

In this procedure, the inside of the abdomen is viewed using a camera with light. The main goal is to identify and ligate the affected veins to restore proper blood flow to the scrotum without damaging critical structures such as arteries and the vas deferens.

Microsurgical Varicocelectomy

Unlike open laparoscopy, this surgery is performed through a smaller incision and involves the use of a microscope. This reduces the risk of complications and improves recovery time.

Varicocele Embolization

Varicocele embolization is a percutaneous treatment performed by cardiovascular or interventional radiology specialists. The goal is to access the enlarged testicular veins from inside the body, stop blood flow, and reduce pressure. This causes the veins to shrink, reduces pain, and may improve sperm quality. However, the recurrence rate is higher compared to surgery.

What Is Microsurgical Varicocelectomy and How Is It Different?

Microsurgical varicocelectomy is a specialized surgical technique used to remove overly dilated and twisted veins (varicocele) around the testicle.

The surgeon makes a small incision near the groin and uses a microscope that magnifies veins 15–20 times to clearly distinguish which veins should be tied off and which arteries and spermatic ducts should be preserved. This ensures that blood is rerouted from problematic veins to healthy ones, maintaining testicular blood flow, preserving the spermatic tract, and protecting lymphatic channels.

This meticulous microsurgical technique “targets” the problematic veins, achieving a high success rate and significantly reducing the risk of pain and infertility.

What Are the Techniques of Microsurgical Varicocelectomy?

There are two microsurgical varicocelectomy approaches based on the incision site:

Inguinal Microsurgical Varicocelectomy: This surgery involves a 3–5 cm incision along the groin (right or left), allowing the surgeon to access the spermatic cord, which contains nerves, arteries, and veins supporting the testicles. Once identified, the cord is pulled outside the body, and the surgeon separates the structures within, identifying and isolating abnormal veins. These veins are either cauterized or closed using stitches or clips.

Subinguinal Microsurgical Varicocelectomy: The subinguinal approach involves a lower incision closer to the scrotum than the inguinal approach. This procedure takes longer because the incision is made in the groin area where the spermatic vein branches into several smaller veins. It offers the surgeon more opportunities to identify various veins and lymphatic channels.

Who Are the Best Candidates for Microsurgical Varicocelectomy?

Microsurgical varicocelectomy is most suitable for men with varicoceles visible or palpable during a physical exam. It is also effective for those experiencing pain due to varicocele, testicular shrinkage (atrophy), or abnormal semen test results.

What Is the Recovery Process After Microsurgical Varicocelectomy?

There will be some pain at the incision site due to stitches. Patients recovering from inguinal microsurgical varicocelectomy may feel more pain since the incision involves the abdominal muscles.

Full recovery is expected within two weeks. Returning to work and light activities usually takes 2 days. However, activities should be as light as possible to allow the incision to heal. Patients should avoid sexual activity for at least one to two weeks.

When Will the Results of Microsurgical Varicocelectomy Be Seen?

This surgery has an 80% success rate in improving sperm count and function. It is similarly effective in relieving pain symptoms.

What Are the Risks and Complications of Varicocelectomy?

As with many surgeries, there are potential risks and complications associated with varicocelectomy procedures. Although rare, serious complications include:

  • Bleeding
  • Infection
  • Blood clots in the leg
  • Injury or damage to the testicle
  • Testicular shrinkage
  • Chronic pain
  • The procedure also carries risks associated with the use of anesthesia.

While the goal of varicocelectomy procedures is to eliminate varicoceles, there is a chance they may recur. It is estimated that 15% of men experience recurrence after surgery.

Studies show that around 60% of men see improved semen quality after this procedure. However, varicocelectomy does not guarantee the treatment of male infertility.

When Should You See a Doctor?

You should contact your doctor if you experience any of the following complications after varicocelectomy:

  • Signs of infection near the incision site
  • High fever
  • Persistent swelling or pain
  • Pain or swelling in the legs
  • Ongoing nausea and vomiting

Frequently Asked Questions About Varicocele

1- Can varicocele cause infertility?

Yes, it can impair sperm production and quality, leading to male infertility.

2- When can I return to sports after microsurgical varicocelectomy?

Light activity is recommended in the first week, full sports activities in the 3rd–4th week.

3- Is non-surgical treatment of varicocele possible?

Although embolization is an option, its success rate is lower than that of microsurgery.

4- Can varicocele recur?

Recurrence rate is 1–2% with the microsurgical technique; higher with other methods.

5- When will sperm parameters improve after surgery?

Significant improvement is usually seen within 3–6 months.

6- Should varicocele be treated during adolescence?

If testicular volume is reduced or pain is present, surgery may be considered.

7- How long does the operation take?

Approximately 30–45 minutes for one side.

8- Is scrotal support necessary after surgery?

Supportive underwear is recommended during the first week.

9- What does varicocele pain feel like?

It is typically a dull, heavy scrotal pain that worsens with standing, exercise, or throughout the day and improves when lying down.

10- What does the testicle look like in varicocele?

On physical examination, twisted veins resembling a “bag of worms” may be felt. In advanced cases, swollen, vein-filled appearance can be seen on the scrotum. Color Doppler ultrasound shows veins dilated ≥3 mm.

11- Who is more likely to develop varicocele?

Common among males aged 15–35, particularly tall, thin individuals, those who stand for long periods, or engage in heavy physical activity. It tends to occur on the left side.

12- What is bilateral varicocele?

Presence of dilated veins in both testicles (right and left). Seen in about 10–15% of cases.

13- Does varicocele affect erection?

It does not directly cause erectile dysfunction. However, in advanced cases, it may slightly lower testosterone levels, which can indirectly affect erection quality.

14- What are the grades of varicocele?

  1. Grade 1: Palpable only during Valsalva maneuver (straining).
  2. Grade 2: Palpable while standing without Valsalva.
  3. Grade 3: Clearly visible while standing, without needing palpation.

15- What happens if varicocele is not treated?

Over time, testicular shrinkage (atrophy), deterioration in sperm count, motility and morphology, resulting infertility, and chronic scrotal discomfort may occur. Rarely, vein thrombosis may develop.

Sources

  • Mayo Clinic
  • Cleveland Clinic
  • European Association of Urology (EAU)
  • American Urological Association (AUA)
  • National Health Service (NHS)
  • Medscape
  • UpToDate
  • Johns Hopkins Medicine
  • National Institutes of Health (NIH)
  • American Society for Reproductive Medicine (ASRM)
  • European Urology
  • Nature Reviews Urology
  • Healthline